Anadenanthera peregrina , also known as yopo , jopo , cohoba , parica or calcium tree , is a perennial tree of the genus Anadenanthera native to the Caribbean and South America.[1] It grows up to 20 m (66 ft) tall, and has a horny bark. Its flowers are pale yellow to white and spherical. It is an entheogen which has been used in healing ceremonies and rituals for thousands of years in South America.[2]